Substance name | EC | CAS | Reason for inclusion | Examples of use(s) |
2-(4-tert-butylbenzyl)propionaldehyde and its individual stereoisomers | – | – | Toxic for reproduction (Article 57 (c)) | Cleaning agents, cosmetics, in scented articles, polishes and wax blends. |
Orthoboric acid, sodium salt | 237-560-2 | 13840-56-7 | Toxic for reproduction (Article 57 (c)) | Not registered under REACH. May be used as solvent and corrosion inhibitor. |
2,2-bis(bromomethyl)propane1,3-diol (BMP); 2,2-dimethylpropan-1-ol, tribromo derivative/3-bromo-2,2-bis(bromomethyl)-1-propanol (TBNPA); 2,3-dibromo-1-propanol (2,3-DBPA) | 221-967-7; 253-057-0; 202-480-9 | 3296-90-0; 36483-57-5; 1522-92-5; 96-13-9 | Carcinogenic (Article 57 (a)) | BMP: manufacture of polymer resins and in one component foam (OCPF) application. TBNPA: polymer production manufacture of plastics products, including compounding and conversion and as an intermediate. DBPA: registered as an intermediate. |
Glutaral | 203-856-5 | 111-30-8 | Respiratory sensitising properties (Article 57(f) – human health) | Biocides, leather tanning, x-ray film processing, cosmetics. |
Medium-chain chlorinated paraffins (MCCP) UVCB substances consisting of more than or equal to 80% linear chloroalkanes with carbon chain lengths within the range from C14 to C17 | – | – | PBT (Article 57 (d)) vPvB (Article 57 (e)) | Flame retardants, plasticising additives in plastics, sealants, rubber and textiles |
Phenol, alkylation products (mainly in para position) with C12-rich branched alkyl chains from oligomerisation, covering any individual isomers and/ or combinations thereof (PDDP) | – | – | Toxic for reproduction (Article 57 (c)) Endocrine disrupting properties (Article 57 (f) – human health and environment) | Preparation of lubricant additive materials and of fuel system cleaners. |
1,4-dioxane | 204-661-8 | 123-91-1 | Carcinogenic (Article 57 (a)) Equivalent level of concern having probable serious effects to the environment (Article 57 (f) -environment) Equivalent level of concern having probable serious effects to human health (Article 57 (f) –human health) | Solvent. |
4,4′-(1-methylpropylidene)bisphenol | 201-025-1 | 77-40-7 | Endocrine disrupting properties (Article 57 (f) – human health and environment) | Not registered under REACH. May be used in manufacture of phenolic and polycarbonate resin. |